Soritene

Tazarotene ·Beximco Pharmaceuticals Ltd.·Cream

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Packages & prices

Pack	Price	Details
25 gm tube	৳	25 gm tube: ৳ 151.00

Administration

For psoriasis: Apply once daily in the evening usually for up to twelve weeks. Use and dose must be determined by the doctor of children upto 12 years of age.

For acne: Cleanse the face gently. After the skin is dry, apply a thin layer of Tazarotene cream once per day, in the evening, to the skin areas where acne lesions appear. Use enough to cover the entire affeted area.

Effects

Generally Soritene cream is well-tolerated .The most frequent adverse events related to treatment with Soritene are skin-related as for example pruritus, erythema, burning, irritation, desquamation, stinging, contact dermatitis, dermatitis, eczema, worsening of psoriasis, skin pain, rash, hypertriglyceridemia, dry skin, skin inflammation, and peripheral edema.

Indications

Soritene 0.1% cream is indicated for the topical treatment of patients with plaque psoriasis. It also works to treat acne.

Pharmacology

Topical Tazarotene blocks ornithine decarboxylase (ODC) activity, which is associated with cell proliferation and hyperplasia. Tazarotene suppresses expression of MRP8, a marker of inflammation present in the epidermis of psoriasis patients at high levels. In human keratinocyte cultures, it inhibits cornified envelope formation, whose build-up is an element of the psoriatic scale. Tazarotene also induces the expression of a gene which may be a growth suppressor in human keratinocytes and which may inhibit epidermal hyperproliferation in treated plaques.

Precautions

Soritene cream should be applied only to the affected areas. It is for external use only. Avoid contact with eyes, eyelids, and mouth. If contact with eyes occurs, rinse thoroughly with water. Retinoid should not be used on eczematous skin, as they may cause severe irritation. Because of heightened burning susceptibility, exposure to sunlight (including sunlamps) should be avoided unless deemed medically necessary and in such cases, exposure should be minimized during the use of Soritene cream. Soritene cream should be administered with caution if the patient is also taking drugs known to be photosensitizers (e.g., thiazides, tetracyclines, fluoroquinolones, phenothiazines, sulfonamides) because of the increased possibility of augmented photosensitivity.