Pylotrip

Lansoprazole + Amoxicillin + Clarithromycin ·Square Pharmaceuticals PLC·Tablet

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Packages & prices

Pack	Price	Details
4 tablet strip	৳	4 tablet strip: BDT 55.16 (14's pack: BDT 772.24)

Administration

Adult dose: One strip twice daily for 7-14 days or as per the physician's advice.

Geriatric use: Elderly patients may suffer from asymptomatic renal and hepatic dysfunction. Care should be taken when administering to these patients.

Effects

Adverse reactions which were reported as possibly or probably related to treatment (>3%) in clinical trials when all three components of this therapy were given concomitantly are listed below and divided by body systems. Digestive system: Nausea, vomiting, diarrhea, dark stools, dry mouth, glossitis, oral moniliasis, stomatitis, tongue discoloration. Musculoskeletal System: myalgia. Nervous System: confusion, headache, dizziness; Skin: skin reactions. Urogenital System: vaginitis,vaginal moniliasis.

Indications

This is indicated for the eradication of H. pylori in active chronic gastric, duodenal and gastric ulcers.

Pharmacology

Lansoprazole is a proton-pump inhibitor which inhibits the stomach's production of gastric acids. Amoxicillin is a penicillin antibiotic. It acts by inhibiting the synthesis of bacterial cell walls.lt inhibits cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell walls of both Gram-positive and Gram-negative bacteria. Clarithromycin is a macrolide antibiotic.It prevents bacteria from growing by interfering with their protein synthesis. It binds to the subunit 50S of the bacterial ribosome and thus inhibits the translation of peptides

Precautions

Serious and occasionally fatal hypersensitivity (anaphylactoid) reactions have been reported in patients on Amoxicillin therapy. These reactions are more appropriate to occur in individuals with a history of penicillin hypersensitivity. Clarithromycin should not be used in pregnant women except in clinical circumstances where no alternative therapy is appropriate.