Oxyzolin

Oxymetazoline Hydrochloride (Nasal Preparation) ·Gaco Pharmaceuticals Ltd.·Nasal Drop

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Packages & prices

Pack	Price	Details
10 ml drop	৳	10 ml drop: BDT 43.00

Administration

Oxymetazoline nasal spray-

Adults and children (6 years of age and older): 2 or 3 sprays in each nostril twice daily for 3-5 days.
Elderly: There is no need for dosage reduction in the elderly for nasal administration.
Children below 6 years of age: It is not suitable for children below 6 years of age.

Oxymetazoline nasal drop-

Adults & children 6 years of age: 2-3 drops of 0.05% Nasal Drops in each nostril twice daily in the morning and evening.
Children 2-5 years of age: 2-3 drops of 0.025% Nasal Drops in each nostril twice daily in the morning and evening

Effects

Occasionally it may cause local irritation and dryness of the mouth and throat. Temporarily discomfort such as burning, stinging, sneezing or increase in nasal discharge may occur.

Overdose may give rise to local irritation and rebound congestion. Treatment need only be symptomatic.

Indications

Oxymetazoline Hydrochlorid is indicated for the treatment of nasal congestion associated with acute or chronic rhinitis, common cold, sinusitis, upper respiratory allergies, epistaxis and hay fever. It is also used as nasal decongestant in otitis media.

Pharmacology

Oxymetazoline Hydrochloride is an imidazoline derivative sympathomimetic amine. It is a direct agonist at α-adrenoceptors but has no action on β- adrenoceptors. It is used as a topical agent on the nasal mucosa, produces a rapid and long acting vasoconstriction of the arterioles, thus reducing the blood flow and diminishing swelling of the mucosa. This results in improved potency of the airway and better drainage of the nasal sinus.

Precautions

Keep away from the eyes. The spray should not be used for longer than seven days without medical advice. Frequent or prolonged use may cause nasal congestion to recur or worsen.