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Ospemifene ·Navana Pharmaceuticals Ltd.·Tablet

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Packages & prices

Pack Price Details
Unit Price ৳ Unit Price: BDT 30.00 (20's pack: BDT 600.00)

Administration

Ospemifene is an estrogen agonist/antagonist which has agonistic effects on the endometrium. Use of Ospemifene should be for the shortest duration consistent with treatment goals and risks for the individual woman. Postmenopausal women should be re-evaluated periodically as clinically appropriate to determine if treatment is still necessary.
  • Treatment of Moderate to Severe Dyspareunia, a Symptom of Vulvar and Vaginal Atrophy, Due to Menopause: Take one 60 mg tablet with food once daily.
  • Treatment of Moderate to Severe Vaginal Dryness, a Symptom of Vulvar and Vaginal Atrophy, Due to Menopause: Take one 60 mg tablet with food once daily.

Effects

Adverse reactions (≥1 percent) include hot flush, vaginal discharge, muscle spasms, headache, hyperhidrosis, vaginal hemorrhage, night sweats.

Indications

Ospemifene is indicated for:
  • The Treatment of Moderate to Severe Dyspareunia, a Symptom of Vulvar and Vaginal Atrophy, Due to Menopause.
  • The Treatment of Moderate to Severe Vaginal Dryness, a Symptom of Vulvar and Vaginal Atrophy, Due to Menopause.

Pharmacology

Ospemifene is an estrogen receptor agonist/antagonist with tissue selective effects. Its biological actions are mediated through binding to estrogen receptors. This binding results in activation of estrogenic pathways in some tissues (agonism) and blockade of estrogenic pathways in others (antagonism).

Precautions

  • Venous Thromboembolism: Risk of DVT and pulmonary embolism
  • Known, suspected, or history of breast cancer
  • Severe Hepatic Impairment

Therapeutic

Drugs used in Vaginal and Vulval condition

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