Optivir

Acyclovir (Ophthalmic) ·Biopharma Limited·Ophthalmic Ointment

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Packages & prices

Pack	Price	Details
5 gm tube	৳	5 gm tube: BDT 100.00

Administration

The dosage for all age groups is the same. A 10 mm ribbon of the ointment should be placed inside the lower conjunctival sac five times a day at approximately four hourly intervals. Treatment should continue for at least 3 days after healing

Effects

Very common: Superficial punctate keratopathy. This did not necessitate an early termination of therapy and healed without apparent sequelae. Common: Transient mild stinging of the eye occurring immediately following application, conjunctivitis. Rare: Blepharitis.

No adverse effects would be expected if the entire contents of the tube containing 90 mg Acyclovir were ingested orally.

Indications

Acyclovir is indicated for the treatment of Herpes simplex keratitis.

Pharmacology

Acyclovir is an antiviral agent which is highly active in vitro against Herpes simplex (HSV) types I and II and Varicella zoster viruses, but its toxicity to mammalian cells is low. Acyclovir is phosphorylated to the active compound Acyclovir triphosphate after entry into herpes infected cell. The first step in this process requires the presence of the viral-coded thymidine kinase. Acyclovir triphosphate acts as an inhibitor of and substrate for the herpes specified DNA polymerase preventing further viral DNA synthesis without affecting normal cellular processes.