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Opthamet

Antazoline + Tetryzoline ·Drug International Ltd.·Ophthalmic Solution

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Packages & prices

Pack Price Details
10 ml drop ৳ 10 ml drop: BDT 110.35

Administration

Adults and adolescents: 1 drop 2 to 3 times daily upto 14 days.

Children (Older than 2 years of age): No specific studies are available in this patient group. For possible systemic effects, the dosage should exceed to 1 to 2 drops per day.

Children (Below 2 years of age): Not to be used in children below 2 years of age.

The eye drop should not be used for longer periods than 14 days as this may cause rebound hyperemia and toxic follicular conjunctivitis.

Effects

The most common adverse effect is burning/stinging upon installation, which is mild and transient in nature.

A topical overdose of this ophthalmic solution may be flushed from the eye with warm tap water.

Indications

Temporary relief of the signs and symptoms of allergic conjunctivitis including conjunctival hyperaemia, chemosis and itching in adults and children above 2 years of age.

Pharmacology

Antazoline is an anti-histamine of the ethylenediamine class, which are selective HI-antagonist. Effects mediated by HI receptors include the contraction of smooth muscle and the dilation and increased permeability of the capillaries. Tetryzoline is a sympathomimetic with alpha-adrenergic activity. Its vasoconstrictive effect reduces redness and edema in allergic conjunctivitis. Antihistamines, which act by blocking the HI histamine receptor, are highly effective in providing relief of itching but are not very active in relieving the associated redness. The use of products combining an anti-histamine and a vasoconstrictor is well established in the symptomatic relief of allergic eye disease.

Precautions

The eye drop should be used with caution in elderly patients with severe cardiovascular disease, including arrhythmia, poorly controlled hypertension or diabetes.

Therapeutic

Other ophthalmic preparations

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