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Cilostazol ·Advanced Chemical Industries PLC·Tablet

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Packages & prices

Pack	Price	Details
Unit Price	৳	Unit Price: BDT 10.00 (20's pack: BDT 200.00)

Administration

The recommended dosage of Cilostazol is 100 mg bid, taken at least half an hour before or two hours after breakfast and dinner. A dose of 50 mg bid should be considered during coadministration of Fluconazole, Ketoconazole, Itraconazole, Erythromycin, Clarithromycin, Fluvoxamine, Fluoxetine, Nefazodone, Sertraline and Diltiazem.

Pediatric use: The safety and effectiveness of Cilostazol in pediatric patients have not been established.

Effects

The most common side effects are headache, diarrhoea, vomiting, leg cramps, rash etc. The less frequent side effects are anorexia and edema.

Indications

Cilostazol is indicated for the reduction of symptoms of intermittent claudication, as indicated by an increased walking distance.

Pharmacology

Cilostazol is a preparation of Cilostazol which is a quinolinone derivative. The mechanism of action is to specifically inhibit cellular phosphodiesterase III (PDE III) and suppress cAMP degradation with a resultant increase in cAMP in platelets and blood vessels, leading to inhibition of platelet aggregation and vasodilation.

Precautions

Cilostazol should be used with caution in patients with any degree of heart failure. There is no information with respect to the efficacy or safety of the concurrent use of Cilostazol and Clopidogrel.