Histosin

Chlorpheniramine Maleate ·Aexim Pharmaceuticals Ltd.·Syrup

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Packages & prices

Pack	Price	Details
100 ml bottle	৳	100 ml bottle: BDT 12.00

Administration

Adult- Usual adult dose is 4 mg every 4-6 hours, maximum 24 mg daily.

Child-

6-12 years: 2 mg every 4-6 hours, maximum 12 mg daily.
2-5 years: 1 mg every 4-6 hours, maximum 6 mg daily.
1-2 years: 1 mg twice daily.

Below 1 year the use of Chlorpheniramine Maleate is not recommended.

Effects

Chlorpheniramine is well-tolerated, but sometimes drowsiness, dizziness, muscular weakness, and gastrointestinal upset may occur.

CNS depression (including sedation, apnea, CV collapse), CNS stimulation (including insomnia, hallucination, tremors, convulsions), tinnitus, blurred vision, dizziness, ataxia, hypotension. Stimulation and atropine-like signs and symptoms (including dry mouth, fixed dilated pupils, flushing, hyperthermia, Gl symptoms) are more likely in children.

Indications

Chlorpheniramine Maleate is indicated in the following indications-

Urticaria
Sensitivity reactions
Angioneurotic edema
Vasomotor rhinitis
Cough
Common cold
Motion sickness and
Other allergic conditions.

Pharmacology

Chlorpheniramine Maleate is an alkylamine antihistamine. It is one of the most potent histamine H1-receptor blocking agents which is used as a potent antihistamine. This generally causes less sedation than promethazine. Chlorpheniramine Maleate exerts its effects by blocking H1-receptor competitively.

Precautions

Chlorpheniramine should be used with caution in patients with glaucoma and prostatic hypertrophy. During therapy with chlorpheniramine, caution should be taken in driving vehicles and operating machinery.