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Glycovent

Glycopyrronium Bromide (Respirator Solution) ·Square Pharmaceuticals PLC·Nebuliser Solution

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Administration

The recommended dose of Glycopyrrolate is the inhalation one ampoule twice-daily. It should be administered at the same time of the day, (1 ampoule in the morning and 1 ampoule in the evening), every day.

Effects

The following adverse reactions are found:
  • shortness of breath,
  • urinary tract infection,
  • wheezing,
  • upper respiratory tract infection,
  • runny nose,
  • fatigue.

An overdose of glycopyrrolate may lead to anticholinergic signs and symptoms such as nausea, vomiting, dizziness, lightheadedness, blurred vision, increased intraocular pressure (causing pain, vision disturbances, or reddening of the eye), obstipation or difficulties in voiding

Indications

Glycopyrrolate is indicated for the long-term maintenance treatment for patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.

Pharmacology

Glycopyrrolate is a long-acting muscarinic antagonist which has similar affinity to the subtypes of muscarinic receptors M1 to M5. In the airways, it exhibits pharmacological effects through inhibition of M3 receptor at the smooth muscle leading to bronchodilation.

Precautions

Glycopyrrolate should not be initiated in patients during acutely deteriorating or potentially life-threatening episodes of COPD. Glycopyrrolate should not be used as rescue therapy for the treatment of acute episodes of bronchospasm.

Therapeutic

Bronchodilator

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