Bufen-SR

Pack	Price	Details
Unit Price	৳ 123.00	Unit Price: ৳ 4.10 (6 x 5: ৳ 123.00)

Ibuprofen Tablet-
1. Mild to moderate pain and fever:
Adults and adolescents >40 kg body weight (12 years and above):

• 200-400 mg given as a single dose or 3-4 times a day with an interval of 6 hours as required.
• In migraine headache, 400 mg should be given as a single dose, if necessary 400 mg with intervals up to 6 hours.
• The maximum daily dose should not exceed 1200 mg.

Children 20 kg body weight (6-11 years)

• Children 20-29 kg (6-9 years): 200 mg 1-3 times a day with intervals of 6 hours as required.
• The maximum daily dose should not exceed 600 mg.
• Children 30-90 kg (10-11 years): 200 mg 1-4 times a day with intervals of 6 hours as required.
• The maximum daily dose should not exceed 800 mg.
• Ibuprofen tablet is contraindicated in children below 20 kg body weight or younger than 6 years of age.

2. Primary dysmenorrhoea:

• Adults and adolescents 40 kg body weight (12 years of age and above) 200-400 mg 1-3 times a day, with an interval up to 6 hours, as needed. The maximum daily dose should not exceed 1200 mg.

3. Rheumatic diseases:

• Adults: The recommended dose is 1200-1800 mg daily in divided doses. Maintenance doses of 600-1200 mg daily may be effective in some patients. In acute and severe conditions the dose may be (temporarily) increased to a maximum of 2400 mg in 3 or 4 divided doses.
• Adolescents from 15 to 17 years of age: The recommended dose should be adjusted by weight: 20 mg/kg to a maximum of 40 mg/kg body weight daily (max 2400 mg daily) in 3 to 4 divided doses.

Ibuprofen SR Capsule-

• Adults, the elderly and children & adolescents between 12 and 18 years
• Initially one (300 mg) or two (600 mg) Ibuprofen SR capsules should be taken twice daily. Not more than 4 capsules are to be taken in 24 hours.
• Ibuprofen SR capsule is not recommended for children below 12 years of age.

Ibuprofen Suspension: Children-

• 3-6 months (body-weight over 5 kg): 1/2 tsp (2.5 ml) 3 times daily
• 6 months-1 year: 0.5 tsp (2.5 ml) 3-4 times daily
• 1-4 years: 1 tsp (5 ml) 3 times daily
• 4-7 years: 1.5 tsp (7.5 ml) 3 times daily
• 7-10 years: 2 tsp (10 ml) 3 times daily
• 10-12 years: 3 tsp (15 ml) 3 times daily
• Not recommended for children weighing less than 5 kg.
• In juvenile rheumatoid arthritis; up to 30-40 mg/kg of body weight daily in 3-4 divided doses may be taken.

The most common side effects are headache, somnolence, vertigo, fatigue, agitation, dizziness, insomnia, irritability and gastrointestinal ulcer.

Bufen-SR is indicated in-

• Relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis
• Treatment of primary dysmenorrhea
• Control of mild to moderate pain generally and particularly when pain is associated with inflammation
• Reduction of fever
• Dental and period pain
• Relief of backache
• Rheumatic pain
• Muscular pain

Ibuprofen has a high level of anti-inflammatory, anti-pyretic, and analgesic activity. The analgesic effects of Ibuprofen are due to both a peripheral and a central effect. Ibuprofen is a potent inhibitor of the enzyme cyclooxygenase, which thus results in a marked reduction in prostaglandin synthesis. Ibuprofen also inhibits the synthesis of some lipo-oxygenase products. Ibuprofen thus quickly relieves pain and stiffness, reduces swelling, and improves the movement of different joints of arthritis sufferers.

Patients on long term therapy with Bufen-SR require ocular monitoring at regular intervals, as changes in ocular function have been reported. Patients with SLE are more likely than others to develop hypersensitivity to Bufen-SR. Bufen-SR should be prescribed with caution in patients with asthma.

Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs)

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