Budicort

Budesonide (Nasal Spray) ·Incepta Pharmaceuticals Ltd.·Nasal Spray

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Packages & prices

Pack	Price	Details
120 metered sprays	৳	120 metered sprays: ৳ 250.00

Administration

Adults and children 6 years of age and older: 100 mcg per day administered as one spray per nostril once daily.

Adults (12 years of age and older): The maximum recommended dose is 400 mcg per day administered as four sprays per nostril once daily.

Pediatric Use: Safety and effectiveness in pediatric patients below 6 years of age have not been established.

Effects

Adverse local reactions following Budicort use are mild and usually transient. Systemic side effects have not been reported during clinical studies of Budicort nasal preparations. Sneezing, headache, sore throat, dry mouth, nausea etc. have been reported as the common side effects.

Indications

Budicort nasal spray is indicated in-

Prophylaxis and treatment of seasonal and perennial allergic rhinitis.
Prophylaxis and treatment of vasomotor rhinitis.
Symptomatic relief of nasal polyposis.
Prevention against nasal polyps after polypectomy.

Pharmacology

Budesonide is a synthetic corticosteroid having potent glucocorticoid activity and weak mineralocorticoid activity. It has approximately a 200-fold higher affinity for the glucocorticoid receptor and a 1000-fold higher topical anti-inflammatory potency than cortisol. Corticosteroids have been shown to have a wide range of inhibitory activities against multiple cell types (e.g. mast cell, eosinophil, neutrophil, macrophage, and lymphocyte) and mediators (e.g. histamine, eicosanoids, leukotriene, and cytokine) involved in allergic mediated inflammation.

Precautions

Budicort nasal spray should be used with caution in patients with active or quiescent tuberculous infection, untreated fungal, bacterial, or systemic viral infections, or ocular herpes simplex infection. Patients with recent nasal septal ulcers, nasal surgery, or nasal trauma should not use a nasal corticosteroid.